AOD 9604

AOD 9604 and HGH Fragment 176-191 differ by one residue, and sellers blur the names. This is the tyrosine form, closed into a ring by a single disulfide bridge, and Titan Core lists its sequence, bridge position and bridged mass so you can check any lab report against them.

AOD 9604
Out of Stock
For Research Purposes Only
Price $29.99
Size:5MG
Lab report (COA) pending for this out-of-stock product. Will be posted when available.
  • Third-Party Tested - (COA) Available
  • Free 2-Day Shipping on Orders $49.99
  • Tyrosine Form, Not Native Frag 176-191

Overview

The AOD 9604 peptide is growth hormone's last 15 residues with a tyrosine added at the front, and its two cysteines lock the chain into a ring. It began as an anti-obesity candidate; labs now study what it does away from the growth hormone receptor. A 2026 Pain paper, testing it as LAT8881, identified its binding partner, LanCL1, with a probe built from its own ring-containing metabolite.

If the Cys7–Cys14 bridge never closes, the chain weighs 1,817.1 Da instead of 1,815.1, and a 2026 Frontiers in Endocrinology review notes AOD 9604 is often labelled "hGH 176-191", a different peptide 16 Da lighter. Purity can't catch either mistake, and two competitor reports we read don't try: one calls identity "confirmed" with no mass, the other runs no mass test. This page lists the sequence, bridge and bridged weight, and each vial's manufacturer LOT matches its lab report. If your LOT's report isn't posted yet, ask Contact Support before opening. Laboratory research only; not for people or animals.

Research Highlights

  • Neuropathic pain models — As LAT8881, it reduced mechanical allodynia in four rodent neuropathy models, from nerve ligation to chemotherapy-induced (Pain, 2026).
  • Clinical-stage pain research — A Phase II postherpetic neuralgia trial of LAT8881 found no treatment difference on its 4-week pain score (International Journal of Molecular Sciences, 2023).
  • Influenza infection models — Given intranasally from day 1, LAT8881 and its metabolite lowered viral loads in influenza-infected mice, while a third peptide did not (Clinical & Translational Immunology, 2023).
  • Shorter fragments — LAT9997, a 6-residue linear piece of the same sequence, also improved survival in influenza-infected mice (Journal of Infectious Diseases, 2024).
  • Anti-doping detection — Dried-blood-spot screening tracks AOD9604 as a doubly charged ion at m/z 907.94, plus its residue 7–16 metabolite (Analytical and Bioanalytical Chemistry, 2020).
  • Sample stability — In blood samples, AOD9604 held for two months at −20 °C but degraded within a week at 4 and 22 °C (Analyst, 2026).

Product Details

  • FORM: Lyophilized powder
  • PURITY: ≥99% (HPLC verified)
  • SEQUENCE: Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe (disulfide bridge Cys7–Cys14)
  • MOLECULAR FORMULA: C₇₈H₁₂₃N₂₃O₂₃S₂
  • MOLECULAR WEIGHT: 1815.1 g/mol
  • CAS NUMBER: 221231-10-3
  • PRESENTATION: 5mg
  • LOT: Manufacturer LOT
  • STORAGE: Store lyophilized at –20°C, protected from light and moisture.

Frequently Asked Questions

A tyrosine-capped fragment of growth hormone's tail, also sold as AOD9604 or Tyr-hGH 177-191, and called LAT8881 in newer papers.

Lipid-metabolism signaling first; newer work uses it to probe LanCL1 in pain and infection models.

No. Native Fragment 176-191 starts with phenylalanine, AOD 9604 with tyrosine. That swap is the 16 Da gap above; only a mass result shows it.

CJC-1295 is a GHRH analog built to signal the pituitary. AOD 9604 is a piece of the hormone's own tail, studied for effects that don't run through the growth hormone receptor.

A common solubility complaint. Haze doesn't prove a vial fake, and a clear solution doesn't prove it real. We don't give preparation directions.

You can buy AOD 9604 peptide here, sequence and bridge spelled out. If it shows out of stock, Contact Support will tell you when the next LOT is ready.

It isn't approved for any use; the Frontiers review notes the FDA placed it in Category 2 of its bulk drug substances list over immunogenicity. Titan Core supplies it to labs only and gives no advice on side effects, dosing or use in people.

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